科研成果

2023

1.    Cao, Y. F. et al. G9a promotes immune suppression by targeting the Fbxw7/Notch pathway in glioma stem cells. CNS neuroscience & therapeutics 29, 2508-2521, doi:10.1111/cns.14191 (2023).

2.    Feng, Y. et al. METTL3 Mediates Epithelial-Mesenchymal Transition by Modulating FOXO1 mRNA N-Methyladenosine-Dependent YTHDF2 Binding: A Novel Mechanism of Radiation-Induced Lung Injury. Adv Sci 10, doi:10.1002/advs.202204784 (2023).

3.    He, Q. et al. Lactoferrin alleviates Western diet-induced cognitive impairment through the microbiome-gut-brain axis. Curr Res Food Sci 7, doi:ARTN 10053310.1016/j.crfs.2023.100533 (2023).

4.    Ji, M. T. et al. The role of mechano-regulated YAP/TAZ in erectile dysfunction. Nature Communications 14, doi:ARTN 375810.1038/s41467-023-39009-z (2023).

5.    Li, D. M. et al. Lactoferrin Alleviates Ethanol-Induced Injury via Promoting Nrf2 Nuclear Translocation in BRL-3A Rat Liver Cells. International journal of molecular sciences 24, doi:ARTN 1684810.3390/ijms242316848 (2023).

6.    Li, M. et al. The vanillin derivative VND3207 protects intestine against radiation injury by modulating p53/NOXA signaling pathway and restoring the balance of gut microbiota (vol 145, pg 223, 2019). Free Radical Bio Med 204, 83-83, doi:10.1016/j.freeradbiomed.2023.04.016 (2023).

7.    Li, W. S. et al. Large-scale ORF screening based on LC-MS to discover novel lncRNA-encoded peptides responding to ionizing radiation and microgravity. Comput Struct Biotec 21, 5201-5211, doi:10.1016/j.csbj.2023.10.040 (2023).

8.    Lu, X. Y. et al. Flexible Bioactive Glass Nanofiber-Based Self-Expanding Cryogels with Superelasticity and Bioadhesion Enabling Hemostasis and Wound Healing. ACS nano 17, 11507-11520, doi:10.1021/acsnano.3c01370 (2023).

9.    Pei, H. L. et al. The Tumorigenic Effect of lncRNA AFAP1-AS1 is Mediated by Translated Peptide ATMLP Under the Control of mA Methylation. Adv Sci 10, doi:ARTN 230031410.1002/advs.202300314 (2023).

10.  Tang, H. Y. et al. Heavy Ion-Responsive lncRNA EBLN3P Functions in the Radiosensitization of Non-Small Cell Lung Cancer Cells Mediated by TNPO1. Cancers 15, doi:ARTN 51110.3390/cancers15020511 (2023).

11.  Tang, L. F. et al. Perillaldehyde Mitigates Ionizing Radiation-Induced Intestinal Injury by Inhibiting Ferroptosis via the Nrf2 Signaling Pathway. Molecular nutrition & food research 67, doi:10.1002/mnfr.202300232 (2023).

12.  Wang, R. R. et al. USP11 plays a critical role in the onset and progression of acute graft-versus-host disease:Novel target for precision therapeutics. Pharmacol Res 189, doi:ARTN 10670710.1016/j.phrs.2023.106707 (2023).

13.  Ye, Z. J. et al. Reprimo (RPRM) as a Potential Preventive and Therapeutic Target for Radiation-Induced Brain Injury via Multiple Mechanisms. International journal of molecular sciences 24, doi:ARTN 1705510.3390/ijms242317055 (2023).

14.  Yin, X. H. et al. CN nanodots inhibits Aβ peptides aggregation pathogenic path in Alzheimer's disease. Nature Communications 14, doi:ARTN 571810.1038/s41467-023-41489-y (2023).

15.  Zhuang, H. Z. et al. The role of m6A methylation in therapy resistance in cancer. Molecular cancer 22, doi:ARTN 9110.1186/s12943-023-01782-2 (2023).

16.  Xu, J. et al. Von Willebrand factor promotes radiation-induced intestinal injury (RIII) development and its cleavage enzyme rhADAMTS13 protects against RIII by reducing inflammation and oxidative stress. Free Radical Bio Med 210, 1-12, doi:10.1016/j.freeradbiomed.2023.11.004 (2024).



2022

1. Gao, R. L. et al. Robust radiosensitization of hemoglobin-curcumin nanoparticles suppresses hypoxic hepatocellular carcinoma. J Nanobiotechnol 20, doi:ARTN 11510.1186/s12951-022-01316-w (2022).

2. Guo, Z., Zhou, G. M. & Hu, W. T. Carcinogenesis induced by space radiation: A systematic review. Neoplasia 32, doi:ARTN 10082810.1016/j.neo.2022.100828 (2022).

3. Lang, Y. et al. Black Phosphorus Quantum Dots Enhance the Radiosensitivity of Human Renal Cell Carcinoma Cells through Inhibition of DNA-PKcs Kinase. Cells 11, doi:ARTN 165110.3390/cells11101651 (2022).

4. Liang, S. Q., Zhou, G. M. & Hu, W. T. Research Progress of Heavy Ion Radiotherapy for Non-Small-Cell Lung Cancer. International journal of molecular sciences 23, doi:ARTN 231610.3390/ijms23042316 (2022).

5. Liu, B. et al. Glioma Stem Cells Upregulate CD39 Expression to Escape Immune Response through SOX2 Modulation. Cancers 14, doi:ARTN 78310.3390/cancers14030783 (2022).

6. Shi, L. et al. Regulation of gut microbiome with redox responsible bacterial cellulose hydrogel for precision chemo-radiotherapy of intestinal cancer. Chem Eng J 446, doi:ARTN 13734010.1016/j.cej.2022.137340 (2022).

7. Shi, X. et al. FLASH X-ray spares intestinal crypts from pyroptosis initiated by cGAS-STING activation upon radioimmunotherapy. Proceedings of the National Academy of Sciences of the United States of America 119, e2208506119, doi:10.1073/pnas.2208506119 (2022).

8. Sun, T. et al. Enhanced radiation-induced immunogenic cell death activates chimeric antigen receptor T cells by targeting CD39 against glioblastoma. Cell Death & Disease 13, doi:ARTN 87510.1038/s41419-022-05319-1 (2022).

9. Xu, Y., Pei, W. W. & Hu, W. T. A Current Overview of the Biological Effects of Combined Space Environmental Factors in Mammals. Frontiers in Cell and Developmental Biology 10, doi:ARTN 86100610.3389/fcell.2022.861006 (2022).

10. Zhang, Y. R. et al. RPRM negatively regulates ATM levels through its nuclear translocation on irradiation mediated by CDK4/6 and IPO11. Iscience 25, doi:ARTN 10511510.1016/j.isci.2022.105115 (2022).

11. Zhao, X. et al. Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING mediated T cell activation. Iscience 25, 104690, doi:10.1016/j.isci.2022.104690 (2022).

12. Zheng, L. J. et al. Ionizing radiation-induced long noncoding RNA CRYBG3 regulates YAP/TAZ through mechanotransduction. Cell Death & Disease 13, doi:ARTN 20910.1038/s41419-022-04650-x (2022).

13. Zhou, H. et al. NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells. Redox Biol 55, doi:ARTN 10241310.1016/j.redox.2022.102413 (2022).

 

2021

1. Feng, Y. et al. The Critical Role of Tetrahydrobiopterin (BH4) Metabolism in Modulating Radiosensitivity: BH4/NOS Axis as an Angel or a Devil. Frontiers in Oncology 11, doi:ARTN 72063210.3389/fonc.2021.720632 (2021).

2. Guo, Z. Y. et al. The long noncoding RNA CRYBG3 induces aneuploidy by interfering with spindle assembly checkpoint via direct binding with Bub3. Oncogene 40, 1821-1835, doi:10.1038/s41388-020-01601-8 (2021).

3. Huang, H. et al. Photoacoustic and magnetic resonance imaging-based gene and photothermal therapy using mesoporous nanoagents. Bioact Mater 9, 157-167, doi:10.1016/j.bioactmat.2021.07.025 (2022).

4. Li, Z. Y. et al. Developing a lncRNA Signature to Predict the Radiotherapy Response of Lower-Grade Gliomas Using Co-expression and ceRNA Network Analysis. Frontiers in Oncology 11, doi:ARTN 62288010.3389/fonc.2021.622880 (2021).

5. Luo, W. R. et al. Particle Therapy for Breast Cancer: Benefits and Challenges. Frontiers in Oncology 11, doi:ARTN 66282610.3389/fonc.2021.662826 (2021).

6. Wu, A. Q. et al. Long Non-Coding RNA CRYBG3 Promotes Lung Cancer Metastasis via Activating the eEF1A1/MDM2/MTBP Axis. International journal of molecular sciences 22, doi:ARTN 321110.3390/ijms22063211 (2021).

7. Xu, Y. et al. Disulfiram Alone Functions as a Radiosensitizer for Pancreatic Cancer Both In Vitro and In Vivo. Frontiers in Oncology 11, doi:ARTN 68369510.3389/fonc.2021.683695 (2021).

8. Xue, J. et al. NF-E2-Related Factor 2 (Nrf2) Ameliorates Radiation-Induced Skin Injury. Frontiers in Oncology 11, doi:ARTN 68005810.3389/fonc.2021.680058 (2021).

9. Xue, X. W. et al. Biological Effects of Space Hypomagnetic Environment on Circadian Rhythm. Front Physiol 12, doi:ARTN 64394310.3389/fphys.2021.643943 (2021).

10. Guo, R. R. et al. Biomimetic 3D bacterial cellulose-graphene foam hybrid scaffold regulates neural stem cell proliferation and differentiation. Colloid Surface B 200, doi:ARTN 11159010.1016/j.colsurfb.2021.111590 (2021).

11. Shi, X. L. et al. NAD plus depletion radiosensitizes 2-DG-treated glioma cells by abolishing metabolic adaptation. Free Radical Bio Med 162, 514-522, doi:10.1016/j.freeradbiomed.2020.11.007 (2021).

12. Hu, S. L. et al. Radiation-induced abscopal reproductive effect is driven by TNF-alpha/p38 MAPK/Rac1 axis in Sertoli cells. Theranostics 11, 5742-5758, doi:10.7150/thno.56853 (2021).

13. Zhao, T. S. et al. Dysbiosis of Gut Microbiota Is Associated With the Progression of Radiation-Induced Intestinal Injury and Is Alleviated by Oral Compound Probiotics in Mouse Model. Front Cell Infect Mi 11, doi:ARTN 71763610.3389/fcimb.2021.717636 (2021).